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Homocysteine

A homocysteine test measures the amount of homocysteine in a sample of your blood. Homocysteine is an amino acid. Amino acids are molecules that your body uses to make proteins.

A homocysteine test is most often used to measure your vitamin B6, B12, and folic acid levels. Because these three vitamins break down homocysteine, not having enough of any of them can cause homocysteine levels to increase.

Source: MedlinePlus, U.S. National Library of Medicine

Normal range

176 published ranges, each from a named source
Normal
0–15 umol/L (varies by lab)ABIM 5–15 · ARUP 0–15 umol/L
Female · 59 y
5.4–15.2 nmol/mL
Female · 60 y
5.4–15.3 nmol/mL
Female · 61 y
5.4–15.4 nmol/mL
Female · 62 y
5.5–15.4 nmol/mL
Female · 63 y
5.5–15.5 nmol/mL
Female · 64 y
5.6–15.5 nmol/mL
Female · 65 y
5.6–15.6 nmol/mL
Female · 66 y
5.7–15.6 nmol/mL
Female · 67 y
5.7–15.7 nmol/mL
Female · 68 y
5.8–15.7 nmol/mL
Female · 69 y
5.9–15.7 nmol/mL
Female · 70 y
6–15.8 nmol/mL
Female · 71 y
6.1–15.8 nmol/mL
Female · 72 y
6.2–15.8 nmol/mL
Female · 73 y
6.3–15.9 nmol/mL
Female · 74 y
6.4–15.9 nmol/mL
Female · 75 y
6.5–15.9 nmol/mL
Female · 76 y
6.6–15.9 nmol/mL
Female · 77 y
6.7–16 nmol/mL
Female · 78 y
6.8–16 nmol/mL
Female · 79 y
6.9–16 nmol/mL
Female · 80 y
7–16 nmol/mL
Female · 81 y
7.1–16 nmol/mL
Female · 82 y
7.2–16 nmol/mL
Female · 83 y
7.2–16 nmol/mL
Female · 84 y
7.3–16 nmol/mL
Female · 85 y
7.3–16 nmol/mL
Female · 85 y+
7.4–16 nmol/mL
Male · 59 y
6.9–16 nmol/mL
Male · 60 y
6.9–16.1 nmol/mL
Male · 61 y
7–16.2 nmol/mL
Male · 62 y
7–16.2 nmol/mL
Male · 63 y
7–16.3 nmol/mL
Male · 64 y
7.1–16.3 nmol/mL
Male · 65 y
7.1–16.3 nmol/mL
Male · 66 y
7.1–16.3 nmol/mL
Male · 67 y
7.2–16.3 nmol/mL
Male · 68 y
7.2–16.3 nmol/mL
Male · 69 y
7.2–16.3 nmol/mL
Male · 70 y
7.3–16.3 nmol/mL
Male · 71 y
7.3–16.3 nmol/mL
Male · 72 y
7.3–16.3 nmol/mL
Male · 73 y
7.3–16.3 nmol/mL
Male · 74 y
7.3–16.3 nmol/mL
Male · 75 y
7.3–16.3 nmol/mL
Male · 76 y
7.3–16.3 nmol/mL
Male · 77 y
7.4–16.3 nmol/mL
Male · 78 y
7.4–16.3 nmol/mL
Male · 79 y
7.5–16.3 nmol/mL
Male · 80 y
7.5–16.3 nmol/mL
Male · 81 y
7.7–16.2 nmol/mL
Male · 82 y
7.8–16.2 nmol/mL
Male · 83 y
7.9–16.2 nmol/mL
Male · 84 y
8–16.2 nmol/mL
Male · 85 y
8.2–16.2 nmol/mL
Male · 85 y+
8.3–16.2 nmol/mL
Ranges from ARUP Laboratories Test Directory, American Board of Internal Medicine (Laboratory Test Reference Ranges), Mayo Clinic Laboratories (Test Catalog).

All source ranges (176)
SourceSexAgeRange
American Board of Internal Medicine (Laboratory Test Reference Ranges) All all ages 5–15 umol/L
ARUP Laboratories Test Directory All all ages 0–15 umol/L
Mayo Clinic Laboratories (Test Catalog) Female ≤ 11 mo 3.1–8.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 1 y – 2 y 3.2–8.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 2 y – 3 y 3.2–8.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 3 y 3.2–8.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 4 y 3.3–8.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 5 y 3.4–8.1 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 6 y 3.5–8.1 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 7 y 3.5–8.1 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 8 y 3.6–8.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 9 y 3.7–8.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 10 y 3.8–8.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 11 y 3.9–8.4 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 12 y 3.9–8.6 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 13 y 4–8.7 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 14 y 4.1–8.8 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 15 y 4.2–8.9 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 16 y 4.2–9.1 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 17 y 4.3–9.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 18 y 4.3–9.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 19 y 4.4–9.5 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 20 y 4.4–9.6 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 21 y 4.4–9.8 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 22 y 4.4–9.9 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 23 y 4.4–10.1 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 24 y 4.4–10.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 25 y 4.4–10.4 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 26 y 4.4–10.6 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 27 y 4.3–10.8 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 28 y 4.3–11 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 29 y 4.3–11.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 30 y 4.3–11.4 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 31 y 4.4–11.6 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 32 y 4.4–11.8 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 33 y 4.4–11.9 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 34 y 4.5–12.1 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 35 y 4.5–12.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 36 y 4.6–12.4 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 37 y 4.6–12.5 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 38 y 4.7–12.7 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 39 y 4.7–12.8 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 40 y 4.8–13 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 41 y 4.8–13.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 42 y 4.8–13.4 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 43 y 4.9–13.5 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 44 y 4.9–13.7 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 45 y 4.9–13.9 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 46 y 4.9–14 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 47 y 4.9–14.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 48 y 5–14.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 49 y 5–14.4 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 50 y 5–14.5 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 51 y 5.1–14.6 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 52 y 5.1–14.7 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 53 y 5.1–14.8 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 54 y 5.2–14.9 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 55 y 5.2–15 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 56 y 5.3–15 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 57 y 5.3–15.1 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 58 y 5.3–15.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 59 y 5.4–15.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 60 y 5.4–15.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 61 y 5.4–15.4 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 62 y 5.5–15.4 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 63 y 5.5–15.5 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 64 y 5.6–15.5 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 65 y 5.6–15.6 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 66 y 5.7–15.6 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 67 y 5.7–15.7 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 68 y 5.8–15.7 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 69 y 5.9–15.7 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 70 y 6–15.8 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 71 y 6.1–15.8 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 72 y 6.2–15.8 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 73 y 6.3–15.9 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 74 y 6.4–15.9 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 75 y 6.5–15.9 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 76 y 6.6–15.9 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 77 y 6.7–16 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 78 y 6.8–16 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 79 y 6.9–16 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 80 y 7–16 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 81 y 7.1–16 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 82 y 7.2–16 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 83 y 7.2–16 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 84 y 7.3–16 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 85 y+ 7.4–16 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Female 85 y 7.3–16 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male ≤ 11 mo 3.2–9.7 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 1 y – 2 y 3.3–9.6 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 2 y – 3 y 3.3–9.6 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 3 y 3.3–9.6 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 4 y 3.4–9.5 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 5 y 3.5–9.4 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 6 y 3.6–9.4 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 7 y 3.7–9.4 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 8 y 3.8–9.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 9 y 3.9–9.4 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 10 y 4.1–9.4 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 11 y 4.3–9.4 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 12 y 4.4–9.5 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 13 y 4.6–9.6 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 14 y 4.8–9.7 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 15 y 5–9.8 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 16 y 5.2–9.9 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 17 y 5.4–10 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 18 y 5.6–10.1 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 19 y 5.7–10.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 20 y 5.9–10.5 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 21 y 6–10.6 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 22 y 6.1–10.8 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 23 y 6.2–11 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 24 y 6.2–11.1 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 25 y 6.3–11.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 26 y 6.3–11.4 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 27 y 6.4–11.6 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 28 y 6.4–11.7 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 29 y 6.4–11.8 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 30 y 6.4–11.9 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 31 y 6.4–12.1 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 32 y 6.4–12.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 33 y 6.4–12.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 34 y 6.4–12.4 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 35 y 6.4–12.6 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 36 y 6.4–12.8 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 37 y 6.4–12.9 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 38 y 6.4–13.1 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 39 y 6.4–13.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 40 y 6.5–13.4 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 41 y 6.5–13.5 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 42 y 6.5–13.7 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 43 y 6.6–13.9 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 44 y 6.6–14 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 45 y 6.6–14.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 46 y 6.7–14.4 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 47 y 6.7–14.5 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 48 y 6.8–14.7 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 49 y 6.8–14.9 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 50 y 6.8–15 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 51 y 6.8–15.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 52 y 6.9–15.4 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 53 y 6.9–15.5 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 54 y 6.9–15.6 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 55 y 6.9–15.7 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 56 y 6.9–15.8 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 57 y 6.9–15.9 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 58 y 6.9–16 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 59 y 6.9–16 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 60 y 6.9–16.1 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 61 y 7–16.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 62 y 7–16.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 63 y 7–16.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 64 y 7.1–16.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 65 y 7.1–16.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 66 y 7.1–16.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 67 y 7.2–16.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 68 y 7.2–16.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 69 y 7.2–16.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 70 y 7.3–16.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 71 y 7.3–16.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 72 y 7.3–16.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 73 y 7.3–16.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 74 y 7.3–16.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 75 y 7.3–16.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 76 y 7.3–16.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 77 y 7.4–16.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 78 y 7.4–16.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 79 y 7.5–16.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 80 y 7.5–16.3 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 81 y 7.7–16.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 82 y 7.8–16.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 83 y 7.9–16.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 84 y 8–16.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 85 y 8.2–16.2 nmol/mL
Mayo Clinic Laboratories (Test Catalog) Male 85 y+ 8.3–16.2 nmol/mL

What moves it

cited guidance. not medical advice
Folate — address deficiency when low · National Institutes of Health - Office of Dietary Supplements
Vitamin b12 — address deficiency when low · National Institutes of Health - Office of Dietary Supplements

What an abnormal result can be associated with

A high result
Hyperhomocystinemia
Associations from LOINC2HPO (Human Phenotype Ontology). This is reference information, not a diagnosis: only a clinician can interpret your result in context.
details
Sample
Serum or plasma · LOINC
Collection
Serum gel tube · 1 mL · Mayo Clinic Laboratories (Test Catalog)
Part of
Amino acids panel · Bryan Johnson Blueprint
Listed under
B Vitamins · Folic Acid
Code
LOINC 13965-9 · umol/L
Also known as
Hcys, Hcyst, HCY, Homocyst(e)ine, Heart Disease
See your own Homocysteine Add a lab report and it is drawn against your lab's range, over time. Upload a Blood Test