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Alkaline phosphatase

An alkaline phosphatase (ALP) test measures the amount of ALP in your blood. ALP is an enzyme, a protein that speeds up certain chemical reactions in your body. ALP is found in all your body tissues, but higher amounts can be found in your liver, bile ducts, and bones. Each part of your body makes a different type of ALP.

An alkaline phosphatase test is often used to screen for or help diagnose diseases of the liver or bones. The test may also help diagnose or monitor other health conditions.

Source: MedlinePlus, U.S. National Library of Medicine

Normal range

87 published ranges, each from a named source
Female · 17 y+
35–104 U/L
Female · 20 y+
40–120 U/L
Female · 51 y – 80 y
49–135 IU/L
Female · 80 y+
48–129 IU/L
Male · 19 y+
40–129 U/L
Male · 20 y+
40–120 U/L
Male · 51 y – 80 y
47–123 IU/L
Male · 80 y+
48–129 IU/L
Ranges from ARUP Laboratories Test Directory, LabCorp Test Directory, Mayo Clinic Laboratories (Pediatric Test Catalog), Mayo Clinic Laboratories (Test Catalog).

All source ranges (87)
SourceSexAgeRange
American Board of Internal Medicine (Laboratory Test Reference Ranges) All all ages 30–120 U/L
ARUP Laboratories Test Directory Female ≤ 30 d 60–320 U/L
ARUP Laboratories Test Directory Female 30 d – 11 mo 70–350 U/L
ARUP Laboratories Test Directory Female 1 y – 3 y 125–320 U/L
ARUP Laboratories Test Directory Female 4 y – 6 y 150–370 U/L
ARUP Laboratories Test Directory Female 7 y – 9 y 150–440 U/L
ARUP Laboratories Test Directory Female 10 y – 11 y 150–530 U/L
ARUP Laboratories Test Directory Female 12 y – 13 y 110–525 U/L
ARUP Laboratories Test Directory Female 14 y – 15 y 55–305 U/L
ARUP Laboratories Test Directory Female 16 y – 19 y 40–120 U/L
ARUP Laboratories Test Directory Female 20 y+ 40–120 U/L
ARUP Laboratories Test Directory Male ≤ 30 d 60–320 U/L
ARUP Laboratories Test Directory Male 30 d – 11 mo 70–350 U/L
ARUP Laboratories Test Directory Male 1 y – 3 y 125–320 U/L
ARUP Laboratories Test Directory Male 4 y – 6 y 150–370 U/L
ARUP Laboratories Test Directory Male 7 y – 9 y 150–440 U/L
ARUP Laboratories Test Directory Male 10 y – 11 y 150–470 U/L
ARUP Laboratories Test Directory Male 12 y – 13 y 160–500 U/L
ARUP Laboratories Test Directory Male 14 y – 15 y 130–530 U/L
ARUP Laboratories Test Directory Male 16 y – 19 y 60–270 U/L
ARUP Laboratories Test Directory Male 20 y+ 40–120 U/L
LabCorp Test Directory Female ≤ 5 d 47–127 IU/L
LabCorp Test Directory Female 6 d – 10 d 29–242 IU/L
LabCorp Test Directory Female 11 d – 20 d 109–357 IU/L
LabCorp Test Directory Female 21 d – 30 d 94–494 IU/L
LabCorp Test Directory Female 30 d – 2 mo 149–539 IU/L
LabCorp Test Directory Female 3 mo – 6 mo 131–452 IU/L
LabCorp Test Directory Female 7 mo – 11 mo 117–401 IU/L
LabCorp Test Directory Female 1 y – 6 y 158–369 IU/L
LabCorp Test Directory Female 7 y – 12 y 150–409 IU/L
LabCorp Test Directory Female 13 y 78–227 IU/L
LabCorp Test Directory Female 14 y 64–161 IU/L
LabCorp Test Directory Female 15 y 56–134 IU/L
LabCorp Test Directory Female 16 y 51–121 IU/L
LabCorp Test Directory Female 17 y 47–113 IU/L
LabCorp Test Directory Female 18 y – 20 y 42–106 IU/L
LabCorp Test Directory Female 21 y – 50 y 41–116 IU/L
LabCorp Test Directory Female 51 y – 80 y 49–135 IU/L
LabCorp Test Directory Female 80 y+ 48–129 IU/L
LabCorp Test Directory Male ≤ 5 d 47–127 IU/L
LabCorp Test Directory Male 6 d – 10 d 29–242 IU/L
LabCorp Test Directory Male 11 d – 20 d 109–357 IU/L
LabCorp Test Directory Male 21 d – 30 d 94–494 IU/L
LabCorp Test Directory Male 30 d – 2 mo 149–539 IU/L
LabCorp Test Directory Male 3 mo – 6 mo 131–452 IU/L
LabCorp Test Directory Male 7 mo – 11 mo 117–401 IU/L
LabCorp Test Directory Male 1 y – 6 y 158–369 IU/L
LabCorp Test Directory Male 7 y – 12 y 150–409 IU/L
LabCorp Test Directory Male 13 y 156–435 IU/L
LabCorp Test Directory Male 14 y 114–375 IU/L
LabCorp Test Directory Male 15 y 88–279 IU/L
LabCorp Test Directory Male 16 y 74–207 IU/L
LabCorp Test Directory Male 17 y 63–161 IU/L
LabCorp Test Directory Male 18 y – 20 y 51–125 IU/L
LabCorp Test Directory Male 21 y – 50 y 47–123 IU/L
LabCorp Test Directory Male 51 y – 80 y 47–123 IU/L
LabCorp Test Directory Male 80 y+ 48–129 IU/L
Mayo Clinic Laboratories (Test Catalog) Female ≤ 17 y 50–117 U/L
Mayo Clinic Laboratories (Test Catalog) Female ≤ 14 d 83–248 U/L
Mayo Clinic Laboratories (Test Catalog) Female ≤ 1 y 122–469 U/L
Mayo Clinic Laboratories (Test Catalog) Female ≤ 13 y 129–417 U/L
Mayo Clinic Laboratories (Test Catalog) Female ≤ 10 y 142–335 U/L
Mayo Clinic Laboratories (Test Catalog) Female ≤ 15 y 57–254 U/L
Mayo Clinic Laboratories (Pediatric Test Catalog) Female ≤ 10 y 142–335 U/L
Mayo Clinic Laboratories (Pediatric Test Catalog) Female ≤ 13 y 129–417 U/L
Mayo Clinic Laboratories (Pediatric Test Catalog) Female ≤ 15 y 57–254 U/L
Mayo Clinic Laboratories (Pediatric Test Catalog) Female ≤ 14 d 83–248 U/L
Mayo Clinic Laboratories (Pediatric Test Catalog) Female ≤ 17 y 50–117 U/L
Mayo Clinic Laboratories (Pediatric Test Catalog) Female ≤ 1 y 122–469 U/L
Mayo Clinic Laboratories (Test Catalog) Female 17 y+ 35–104 U/L
Mayo Clinic Laboratories (Pediatric Test Catalog) Female 17 y+ 35–104 U/L
Mayo Clinic Laboratories (Test Catalog) Male ≤ 1 y 122–469 U/L
Mayo Clinic Laboratories (Test Catalog) Male ≤ 13 y 129–417 U/L
Mayo Clinic Laboratories (Test Catalog) Male ≤ 19 y 55–149 U/L
Mayo Clinic Laboratories (Test Catalog) Male ≤ 17 y 82–331 U/L
Mayo Clinic Laboratories (Test Catalog) Male ≤ 14 d 83–248 U/L
Mayo Clinic Laboratories (Test Catalog) Male ≤ 15 y 116–468 U/L
Mayo Clinic Laboratories (Test Catalog) Male ≤ 10 y 142–335 U/L
Mayo Clinic Laboratories (Pediatric Test Catalog) Male ≤ 14 d 83–248 U/L
Mayo Clinic Laboratories (Pediatric Test Catalog) Male ≤ 19 y 55–149 U/L
Mayo Clinic Laboratories (Pediatric Test Catalog) Male ≤ 17 y 82–331 U/L
Mayo Clinic Laboratories (Pediatric Test Catalog) Male ≤ 1 y 122–469 U/L
Mayo Clinic Laboratories (Pediatric Test Catalog) Male ≤ 15 y 116–468 U/L
Mayo Clinic Laboratories (Pediatric Test Catalog) Male ≤ 10 y 142–335 U/L
Mayo Clinic Laboratories (Pediatric Test Catalog) Male ≤ 13 y 129–417 U/L
Mayo Clinic Laboratories (Test Catalog) Male 19 y+ 40–129 U/L
Mayo Clinic Laboratories (Pediatric Test Catalog) Male 19 y+ 40–129 U/L

What an abnormal result can be associated with

A high result
Elevated circulating alkaline phosphatase concentration
A low result
Decreased circulating alkaline phosphatase activity
Associations from LOINC2HPO (Human Phenotype Ontology). This is reference information, not a diagnosis: only a clinician can interpret your result in context.
details
Sample
Serum or plasma · LOINC
Collection
Serum gel tube · 1 mL · Mayo Clinic Laboratories (Test Catalog)
Part of
Comprehensive metabolic panel · Hepatic function panel
Listed under
Bile Duct Cancer · Bile Duct Diseases · Bone Diseases · Cirrhosis · Gallbladder Cancer · Hemochromatosis · Hepatitis · Hepatitis A · Hepatitis B · Hepatitis C · Jaundice · Liver Cancer
Code
LOINC 6768-6 · U/L
Also known as
ALKP, Alk phos, Alkaline phos, ALP, AP
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